Onco Gen

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Metastatic cells: moving onco-targets

Breast cancer is the most frequent malignant neoplasm occurring in women, and metastasis of breast cancer is the main cause of death in these patients [1]. Metastasis is a complicated, multi-step process that is still poorly understood. In reality, for most patients, we just do not know whether they will develop metastasis, and therefore, as a precaution patients are overtreated. In the last de...

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The Future of Onco-Cardiology

About 1 660 000 people, including more than 12 000 children below the age of 18 years, are newly diagnosed with a malignancy in the United States every year. The American Cancer Society reported that in 2016 there are 15.5 million cancer survivors in the United States (http://www.cancer.org/ cancer/news/news/report-number-of-cancer-survivors-continues-to-grow). At present, the 5-year survival r...

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Onco-nephrology: tumor lysis syndrome.

Tumor lysis syndrome (TLS) describes the clinical and laboratory sequelae that result from the rapid release of intracellular contents of dying cancer cells. It is characterized by the release of potassium, phosphorous, and nucleic acids from cancer cells into the blood stream, with the potential to cause hyperkalemia; hyperphosphatemia and secondary hypocalcemia; hyperuricemia; AKI; and, shoul...

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Onco-nephrology: Core Curriculum 2015.

From Zablocki VAMC, Medical College of Wisconsin, Milwaukee, WI; CHU Université de Liège, Liège, Belgium; Hôpital de la Salpetrière, Paris, France; and Katholieke Universiteit Leuven, Leuven, Belgium. Received January 20, 2015. Accepted in revised form April 6, 2015. Originally published online June 6, 2015. Current affiliation: Baltimore VAMC and the University of Maryland School of Medicine, ...

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rk ing in onco l ogy

Care of cancer patients may be a source of considerable stress. As part of a large scale longitudinal study of the interaction of biological, psychological and environmental factors in determining patient outcome, the mental and physical health status of 37 members of the nursing staff of a cancer hospital was examined. The study identifies risk factors for stress, professional ‘burn-out’ and p...

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ژورنال

عنوان ژورنال: Nature

سال: 1982

ISSN: 0028-0836,1476-4687

DOI: 10.1038/300582a0